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Hsp90-IN-15

Products Details

Product Description

– Hsp90-IN-15 is an Hsp90 inhibitor with anticancer activity. Hsp90-IN-15 induces cell apoptosis, arrests the cell cycle at S phase and decreases the expression level of Hsp90 in Hela cell[1].

Web ID

– HY-150655

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C23H27F3N4

References

– [1]Xu Y, et al. New modification strategy of matrine as Hsp90 inhibitors based on its specific L conformation for cancer treatment. Bioorg Med Chem. 2020 Feb 15. 28(4):115305.

CAS Number

– 2252283-32-0

Molecular Weight

– 416.48

SMILES

– [H][C@@]12CCCN3CCC[C@@]([C@@]31[H])([C@]4(CCC5=C(C6=C(N=C5N4C2)C=CC(C(F)(F)F)=C6)N)[H])[H]

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– HSP

Isoform

– HSP90

Pathway

– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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