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Products Details
Product Description
– HSP90-IN-14 (compound 4) is a potent Hsp90 (heat shock protein 90) inhibitor, with a Kd of 0.26 μM. HSP90-IN-14 shows anti-influenza virus activity in MDCK cells, with EC50 values of 2.6, 3.9, and 17 μM for influenza A/H3N2, A/H1N1, and B, respectively[1].
Web ID
– HY-147974
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C14H8Cl2N4O4S
References
– [1]Lamut A, et al. Anti-influenza virus activity of benzo[d]thiazoles that target heat shock protein 90. Bioorg Chem. 2020 May;98:103733.
CAS Number
– 1995132-67-6
Molecular Weight
– 399.21
SMILES
– O=C(O)C(NC1=CC=C2N=C(NC(C3=CC(Cl)=C(Cl)N3)=O)SC2=C1)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HSP;Influenza Virus
Isoform
– HSP90
Pathway
– Anti-infection;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
