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Products Details
Product Description
– HSK205 is a dual FLT3 and haspin inhibitor, with IC50 of 0.187 nM for FLT3. HSK205 has antitumor activity[1].
Web ID
– HY-155341
Shipping
– Room temperature
Molecular Formula
– C26H24N6O
References
– [1]Allison L Kempen, et al. Dual FLT3/haspin kinase inhibitor based on 3 H-pyrazolo[4,3- f]quinoline scaffold with activities against acute myeloid leukemia. RSC Med Chem. 2023 Jul 14;14(9):1743-1754.
Molecular Weight
– 436.51
SMILES
– O=C(NCC1=NC(C)=CN1)C(C=C2)=CC=C2C(C3=C4CCCC3)=NC5=C4C(C=NN6)=C6C=C5
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– FLT3
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
