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HPK1-IN-8
$750 – $3,850
Products Details
Product Description
– HPK1-IN-8 is an allosteric, inactive conformation-selective inhibitor of full-length HPK1.
Web ID
– HY-132926
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H17FN6O2S
References
– [1]Wang W, et al. Discovery of an Allosteric, Inactive Conformation-Selective Inhibitor of Full-Length HPK1 Utilizing a Kinase Cascade Assay. Biochemistry. 2021 Oct 19;60(41):3114-3124.
CAS Number
– 1214561-09-7
Molecular Weight
– 412.44
Compound Purity
– 98.56
SMILES
– O=C(NC1=NC=C(CC2=CC=CC=C2F)S1)CC3=C(C)N=C(NN=C4C)N4C3=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 10 mg/mL (ultrasonic)
Target
– MAP4K
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
