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Products Details
Product Description
– HPK1-IN-36 (compound 2) is a potent HPK1 inhibitor with an IC50 value of 0.5 nM[1].
Web ID
– HY-153448
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H24ClF3N6O2
References
– [1]Omar Ahmad, et al. Isoindolone compounds as hpk1 inhibitors. WO2021224818A1.
Molecular Weight
– 496.91
SMILES
– O=C1C2=CC(OC)=CC(CNC)=C2CN1C3=NC(C4=NN=CN4[C@H](CC(F)(F)F)C)=CC=C3.Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MAP4K
Isoform
– MAP4K1/HPK1
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
