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Products Details
Product Description
– HPK1-IN-27 is a potent inhibitor of HPK1. MAP4K1 is also known as hematopoietic progenitor kinase 1 (HPK1). MAP4K1 is a serine/threonine kinase and member of the germinal center kinase family. HPK1-IN-27 has the potential for the research of cancer diseases (extracted from patent WO2019016071A1, compound 38)[1].
Web ID
– HY-143868
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C26H23F3N4O4
References
– [1]Jeffrey Stuart MOWAT, et al. Substituted pyrrolopyridine-derivatives. Patent WO2019016071A1.
CAS Number
– 2268794-52-9
Molecular Weight
– 512.48
SMILES
– OCC1(C)CN=C(NC2=CC(F)=C(OC3=C4C(NC=C4C5=CC=C(OC)C=C5F)=NC=C3)C(F)=C2)OC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MAP4K
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
