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Products Details
Product Description
– HPK1-IN-25 (example 94) is a hematopoietic progenitor kinase 1 (HPK1) inhibitor with a enzymatic activity IC50 of 129 nM. HPK1-IN-25 has the potential for cancer research[1].
Web ID
– HY-144092
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H25N5O
References
– [1]Jing Li, et al. Pyrrolo [2, 3-b] pyridines or pyrrolo [2, 3-b] pyrazines as hpk1 inhibitor and the use thereof. WO2019238067A1.
CAS Number
– 2403600-50-8
Molecular Weight
– 387.48
SMILES
– COC(C=C1)=CC=C1C2=CNC3=NC=C(C4=CN(C5CCN(CC5)C)N=C4)C=C32
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MAP4K
Isoform
– MAP4K1/HPK1
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
