Products Details

Product Description

– HPK1-IN-24 (example 51) is a hematopoietic progenitor kinase 1 (HPK1) inhibitor with a Ki of 100 nM. HPK1-IN-24 has the potential for cancer research[1].

Web ID

– HY-144091

Shipping

– Room temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C19H14FN5

References

– [1]Oleg VECHORKIN, et al. 6-cyano-indazole compounds as hematopoietic progenitor kinase 1 (hpk1) modulators。 WO2019051199A1.

CAS Number

– 2294966-07-5

Molecular Weight

– 331.35

SMILES

– N#CC1=CC2=C(C=C1C3=C(C=CC=C3C)F)C(C4=CN(C)N=C4)=NN2

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– MAP4K

Isoform

– MAP4K1/HPK1

Pathway

– MAPK/ERK Pathway

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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