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Products Details
Product Description
– HPK1-IN-15 is a potent and selective inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPKl) originally cloned from hematopoietic progenitor cells is a member of MAP kinase kinase kinase kinases (MAP4Ks) family. HPK1-IN-15 is useful in researching, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer (extracted from patent WO2018049200A1, compound 50)[1].
Web ID
– HY-145041
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C24H21ClF3N5
References
– [1]Hai-Fen Ye, et al. Pyrazolopyridine derivatives as hpk1 modulators and uses thereof for the treatment of cancer. Patent WO2018049200A1.
CAS Number
– 2201098-03-3
Molecular Weight
– 471.91
SMILES
– FC(F)(C1=CC=CC(Cl)=C1C2=CC3=C(NN=C3C4=CC=C(N5CCN(CC5)C)C=C4)C=N2)F
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– MAP4K
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
