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Products Details
Product Description
– HPK1-IN-12 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-12 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 85) [1].
Web ID
– HY-145038
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H24FN5O2
References
– [1]Xie, Yuli, et al. Hpk1 inhibitor and preparation method and use thereof. Patent WO2021213317A1.
CAS Number
– 2734168-51-3
Molecular Weight
– 445.49
SMILES
– FC1=C(C2=NC3=C(C=C2)NN=C3C4=CC(OCC5N6CCN(C5)C)=C6C=C4)C(OC)=CC=C1
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– MAP4K
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
