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Products Details
Product Description
– HPB (HDAC6 inhibitor HPB) is a selective HDAC6 inhibitor with an IC50 of 31 nM. HPB exhibits >30-flod selectivity for HDAC6 over HDAC1[1].
Web ID
– HY-130493
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H20N2O4
References
– [1]Nicholas J Porter, et al. Unusual zinc-binding mode of HDAC6-selective hydroxamate inhibitors. Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):13459-13464.
CAS Number
– 1800066-24-3
Molecular Weight
– 328.36
SMILES
– O=C(N(CC1=CC=C(C(NO)=O)C=C1)CCO)CC2=CC=CC=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HDAC
Isoform
– HDAC1;HDAC6
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
