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Products Details
Product Description
– HPA-IN-2 (Compound 2a-1) is a potent and selective human pancreatic α-amylase (HPA) inhibitor with IC50 values of 8.2 μM and 450.7 μM against HPA and α-glucosidase, respectively[1].
Web ID
– HY-143269
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C33H36N4O10
References
– [1]Chen W, et al. Design and synthesis of epigallocatechin (EGC) analogs selective to inhibit α-amylase over α-glucosidases via the incorporation of caffeine acid and its derivatives. Bioorg Chem. 2022 Feb;119:105515.
CAS Number
– 2885971-91-3
Molecular Weight
– 648.66
SMILES
– O=C(NCC1=CN(N=N1)CCCCCCO[C@@H]2CC3=CC(O)=CC(O)=C3O[C@@H]2C4=CC(O)=C(C(O)=C4)O)/C=C/C5=CC=C(C(O)=C5)O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Amylases;Glucosidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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