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HPA-IN-1
SKU
HY-143268-Get quote
Category Reference compound
Tags Amylases;Glucosidase, Metabolic Disease, Metabolic Enzyme/Protease
Products Details
Product Description
– HPA-IN-1 (Compound 1) is a potent and selective human pancreatic α-amylase (HPA) inhibitor with IC50 values of 12.0 μM and 410.4 μM against HPA and α-glucosidase, respectively[1].
Web ID
– HY-143268
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C33H32N4O11
References
– [1]Chen W, et al. Design and synthesis of epigallocatechin (EGC) analogs selective to inhibit α-amylase over α-glucosidases via the incorporation of caffeine acid and its derivatives. Bioorg Chem. 2022 Feb;119:105515.
Molecular Weight
– 660.63
SMILES
– O=C(NCC1=CN(N=N1)CCCCCCOC2=C(OC3=C(C=C(C=C3C2=O)O)O)C4=CC(O)=C(C(O)=C4)O)/C=C/C5=CC=C(C(O)=C5)O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Amylases;Glucosidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.