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Products Details
Product Description
– Homouridine, is an uridine analogue. Homouridine serves as an intermediate to prepare MMP-2 inhibitor (compund I, IC50=150 μM). Homouridine derivate (compund I) also inhibits TNF-α binding to TNF-αR1[1].
Web ID
– HY-154698
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C10H14N2O6
References
– [1]Hsu Li-Wei, et al. Uridine derivatives as matrix metalloproteinase (MMP) and tumor necrosis factor (TNF) inhibitors for the treatment of cancer. European Patent Organization, EP1338282 A1. 2003-08-27.
CAS Number
– 30685-57-5
Molecular Weight
– 258.23
SMILES
– O[C@@H]1[C@H](O)[C@@H](CCO)O[C@H]1N(C(N2)=O)C=CC2=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
