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HIV-IN-9
SKU
HY-156330-Get quote
Category Reference compound
Tags Anti-infection;Metabolic Enzyme/Protease, Cytochrome P450;HIV, Infection
Products Details
Product Description
– HIV-IN-9 (Compound 2b) is a HIV inhibitor (IC50: 6.65 μg/mL), and has high binding affinity with HIV-RT. HIV-IN-9 also inhibits CYP3A4, CYP1A2, CYP2C1, and CYP2D6[1].
Web ID
– HY-156330
Shipping
– Room temperature
Molecular Formula
– C20H15ClN4O3
References
– [1]Srivastava R, et al. Exploring antiviral potency of N-1 substituted pyrimidines against HIV-1 and other DNA/RNA viruses: Design, synthesis, characterization, ADMET analysis, docking, molecular dynamics and biological activity. Comput Biol Chem. 2023 Oct;106:107910.
Molecular Weight
– 394.81
SMILES
– O=C(N1)C(C)=CN(CC(N2C(C3=CC=C(Cl)C=C3)=NC4=CC=CC=C42)=O)C1=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Cytochrome P450;HIV
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.