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HIV-1 protease-IN-5
SKU
HY-147650-Get quote
Category Reference compound
Tags Anti-infection;Metabolic Enzyme/Protease, HIV Protease, Infection
Products Details
Product Description
– HIV-1 protease-IN-5 (Compound 13c) is a HIV-1 protease inhibitor with an IC50 of 1.64 nM. HIV-1 protease-IN-5 shows remarkable activity against wild-type and DRV-resistant HIV-1 variants[1].
Web ID
– HY-147650
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C27H29F3N2O7S
References
– [1]Zhu M, et al. Design and biological evaluation of novel HIV-1 protease inhibitors with isopropanol as P1′ ligand to enhance binding with S1′ subsite. Bioorg Med Chem. 2020 Aug 15;28(16):115623.
CAS Number
– 2525173-96-8
Molecular Weight
– 582.59
SMILES
– C[C@H](CN(S(=O)(C1=CC=C(C=C1)C(F)(F)F)=O)C[C@H]([C@@H](NC(C2=CC(O)=C(C=C2)O)=O)CC3=CC=CC=C3)O)O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV Protease
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.