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Products Details
Product Description
– HIV-1 protease-IN-3 (compound 14) is a potent inhibitor of HIV-1 protease (IC50=71 nM; EC50=0.86 μM)[1].
Web ID
– HY-146804
Shipping
– Room temperature
Molecular Formula
– C27H37NO7S
References
– [1]Kojima E, et al. Pocket-to-Lead: Structure-Based De Novo Design of Novel Non-peptidic HIV-1 Protease Inhibitors Using the Ligand Binding Pocket as a Template. J Med Chem. 2022 Apr 28;65(8):6157-6170.
Molecular Weight
– 519.65
SMILES
– O=C1[C@@](C2=CC=C(S(C)(=O)=O)C=C2O[C@@H](C)CO)(CCC(C)C)[C@@H](O)CN1CC3=CC=C(OC)C=C3
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV;HIV Protease
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
