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Products Details
Product Description
– HIV-1 protease-IN-10 (Compound 2) has HIV-1 latency reversing activity (IC50: 0.22 μM). HIV-1 protease-IN-10 binds to the PKCδ C1b domain (IC50: 0.69 μM). HIV-1 protease-IN-10 has stability against esterase-mediated hydrolysis[1].
Web ID
– HY-155599
Shipping
– Room temperature
Molecular Formula
– C23H40O5
References
– [1]Ishii T, et al. Synthesis and evaluation of DAG-lactone derivatives with HIV-1 latency reversing activity. Eur J Med Chem. 2023 Aug 5;256:115449.
Molecular Weight
– 396.56
SMILES
– O=C1OC(CO)(COC(C(CCCCCC)CCCCCC)=O)C/C1=C(C)/C
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV;PKC
Pathway
– Anti-infection;Epigenetics;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
