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Products Details
Product Description
– HIV-1 inhibitor-43 is a potent HIV-1 inhibitor with an EC50 of 21.3 nM, 6.2 nM, < 0.7 nM and < 0.7 nM for Y188L, K103N-Y181C, K103N and Y181C, respectively. HIV-1 inhibitor-43 can reduce HIV-1 RNA and protein p24 expression[1].
Web ID
– HY-150599
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C24H21ClN2O4S
References
– [1]Nalli M, et al. New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains. Eur J Med Chem. 2020 Dec 15;208:112696.
CAS Number
– 2493426-43-8
Molecular Weight
– 468.95
SMILES
– O=C(C(N1)=C(S(=O)(C2=CC(C)=CC(C)=C2)=O)C3=C1C=CC(Cl)=C3)NCC4=CC=CC=C4O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis;HIV
Isoform
– HIV-1
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
