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Products Details
Product Description
– HIV-1 inhibitor-29 (compound 14d2) is a potent HIV-1 inhibitor with an EC50 of 2.18 μM for HIV-1 IIIB. HIV-1 inhibitor-29 has high anti-resistance profile toward F227L/V106A strain (EC50 = 0.974 μM), and exhibits low cytotoxicity in MT-4 cells (CC50 = 211 μM). HIV-1 inhibitor-29 can be used for researching AIDS[1].
Web ID
– HY-146353
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C30H36N6O5
References
– [1]Wang Z, Kang D, Feng D, et al. Targeting dual tolerant regions of binding pocket: Discovery of novel morpholine-substituted diarylpyrimidines as potent HIV-1 NNRTIs with significantly improved water solubility. Eur J Med Chem. 2020;206:112811.
CAS Number
– 2642217-95-4
Molecular Weight
– 560.64
SMILES
– COC1=CC2=NC(NC3CCN(CC3)CC(N4CCOCC4)=O)=NC(OC5=C(C=C(C=C5C)C#N)C)=C2C=C1OC
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– HIV
Isoform
– HIV-1
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
