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Products Details
Product Description
– HIV-1 inhibitor-23 (compound 12a) is a highly potent HIV-1 non-nucleoside reverse transcriptase inhibitor, with EC50s of 24.9 nM and 10.4 nM for HIV-1 WT and HIV-1 K103N, respectively. HIV-1 inhibitor-23 has low cytotoxicity (CC50 > 221 μM) and a favorable in vitro microsomal stability[1].
Web ID
– HY-146018
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C30H26N6O4S
References
– [1]Han S, et al. Fragment hopping-based discovery of novel sulfinylacetamide-diarylpyrimidines (DAPYs) as HIV-1 nonnucleoside reverse transcriptase inhibitors. Eur J Med Chem. 2020;185:111874.
CAS Number
– 2554622-28-3
Molecular Weight
– 566.63
SMILES
– O=C(NC1=CC=C(C#N)C=C1)CS(C2=NC(NC3=C(C)C=C(/C=C/C#N)C=C3C)=C4C=C(OC)C(OC)=CC4=N2)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV
Isoform
– HIV-1
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
