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Products Details
Product Description
– HIV-1 inhibitor-14 (compound 14b) is a highly potent and broad-spectrum HIV-1 non-nucleoside reverse transcriptase (RT) inhibitor with an EC50 of 0.14 μM for HIV-1 RT. HIV-1 inhibitor-14 has inhibitory activity against HIV-1 WT and resistant strains with EC50s of 5.79 ~ 28.3 nM[1].
Web ID
– HY-144113
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C29H32N6O4S
References
– [1]Kang D, et al. Development of Novel Dihydrofuro[3,4-d]pyrimidine Derivatives as HIV-1 NNRTIs to Overcome the Highly Resistant Mutant Strains F227L/V106A and K103N/Y181C. J Med Chem. 2022;65(3):2458-2470.
CAS Number
– 2761172-65-8
Molecular Weight
– 560.67
SMILES
– CC1=CC(/C=C/C#N)=CC(C)=C1OC2=C3COCC3=NC(NC4CCN(CC4)C5=CC=C(C=C5)NS(=O)(C)=O)=N2
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV
Isoform
– HIV-1
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
