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Histone Acetyltransferase Inhibitor II
$92 – $858
Products Details
Product Description
– Histone Acetyltransferase Inhibitor II (compound 2c) is a potent, selective and cell permeable p300 histone acetyltransferase inhibitor, with an IC50 of 5 µM. Histone Acetyltransferase Inhibitor II shows anti-acetylase activity in mammalian cells[1].
Web ID
– HY-100734
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H16Br2O3
References
– [1]Costi R, et al. Cinnamoyl compounds as simple molecules that inhibit p300 histone acetyltransferase. J Med Chem. 2007 Apr 19;50(8):1973-7. Epub 2007 Mar 10.
CAS Number
– 932749-62-7
Molecular Weight
– 464.15
Compound Purity
– 99.01
SMILES
– O=C1/C(CCC/C1=CC2=CC=C(O)C(Br)=C2)=C/C3=CC=C(O)C(Br)=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 30 mg/mL
Target
– Histone Acetyltransferase
Isoform
– CBP/p300;TIP60
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
