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Products Details
Product Description
– HIF-PHD-IN-2 (compound 25) is a potent PHD inhibitor with IC50s of <100 nM for PHD1, PHD2 and PHD3, respectively[1].
Web ID
– HY-139993
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C17H15N5O3S
References
– [1]Sabnis RW. Novel Compounds as PHD Inhibitors for Treating Heart, Lung, Liver, and Kidney Diseases. ACS Med Chem Lett. 2021;12(12):1868-1869. Published 2021 Nov 4.
CAS Number
– 2711720-45-3
Molecular Weight
– 369.40
SMILES
– OC1=C(C=NN1C2=NC=C(NS(=O)(CC)=O)C=C2)C3=CC=C(C#N)C=C3
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– HIF/HIF Prolyl-Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
