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Products Details
Product Description
– HIF-1/2α-IN-2 is an inhibitor of HIF-1/2α. HIF-1/2α-IN-2 decrease HIF-1/2α levels and induces iron starvation response by targeting Iron Sulfur Cluster Assembly 2 (ISCA2)[1].
Web ID
– HY-151344
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C16H11FN4O2S
References
– [1]Green YS, et al. ISCA2 inhibition decreases HIF and induces ferroptosis in clear cell renal carcinoma. Oncogene. 2022 Sep 12.
CAS Number
– 862974-22-9
Molecular Weight
– 342.35
SMILES
– COC1=C2N=C(NC3=NN=C(C4=CC=C(F)C=C4)O3)SC2=CC=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HIF/HIF Prolyl-Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
