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Products Details
Product Description
– HIF-1α-IN-3 (Compound (S)-3f) is a hypoxia-selective HIF-1α inhibitor. HIF-1α-IN-3 shows strong antiestrogenic potency[1].
Web ID
– HY-147813
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H17N5O2
References
– [1]Buravchenko GI, et al. Discovery of derivatives of 6(7)-amino-3-phenylquinoxaline-2-carbonitrile 1,4-dioxides: novel, hypoxia-selective HIF-1α inhibitors with strong antiestrogenic potency. Bioorg Chem. 2020 Nov;104:104324.
CAS Number
– 2170715-64-5
Molecular Weight
– 347.37
SMILES
– N#CC1=C(C2=CC=CC=C2)[N+]([O-])=C3C=CC(N4C[C@@H](N)CC4)=CC3=[N+]1[O-]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HIF/HIF Prolyl-Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
