HG6-64-1

SKU HY-12291-10 mg Category Tags , ,

$420$2,520

Products Details

Product Description

– HG6-64-1 is a potent and selective B-Raf inhibitor extracted from patent WO 2011090738 A2, example 9 (XI-1); has a IC50 of 0.09 μM on B-raf V600E transformed Ba/F3 cells.

Web ID

– HY-12291

Storage Temperature

– 4°C (Powder, protect from light, stored under nitrogen)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C32H34F3N5O2

References

– [1]WO 2011090738 A2

CAS Number

– 1315329-43-1

Molecular Weight

– 577.64

Compound Purity

– 98.0

SMILES

– O=C(NC1=CC=C(CN2CCN(CC)CC2)C(C(F)(F)F)=C1)C3=CC=C(C)C(/C=C/C4=CN=C(NC=C5)C5=C4OC)=C3

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : ≥ 100 mg/mL

Target

– Raf

Isoform

– BRaf

Pathway

– MAPK/ERK Pathway

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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