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Products Details
Product Description
– HER2-IN-7 is a potent inhibitor of HER2. Deregulation of ErbB family signalling modulates proliferation, invasion, metastasis, angiogenesis, and tumour cell survival. HER2-IN-7 has the potential for the research of diseases associated ErbBs (especially HER2), including cancer (extracted from patent WO2019214634A1, compound 23)[1].
Web ID
– HY-143874
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C28H26F3N7O3
References
– [1]Zhengtao LI, et al. Erbb receptor inhibitors. Patent WO2019214634A1.
CAS Number
– 2387574-01-6
Molecular Weight
– 565.55
SMILES
– COC1=C(OC2C(F)(F)CN(C)CC2)C3=C(NC4=CC=C(OC5=CC6=NC=NN6C=C5F)C(C)=C4)N=CN=C3C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– EGFR
Pathway
– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
