Download Files:
HEPPS
SKU
HY-D0873-25 g
Category Biochemical Assay Reagents
Tags Amyloid-β, Neurological Disease, Neuronal Signaling
$50 – $80
Products Details
Product Description
– HEPPS (EPPS) is a buffering agent with the useful pH range from 7.3 ~ 8.7. HEPPS reduces Aβ-aggregate-induced memory deficits and rescues cognitive deficits in mice. EPPS is orally active and penetrates the blood-brain barrier[1].
Web ID
– HY-D0873
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C9H20N2O4S
References
– [1]Kim HY, et al. EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques. Nat Commun. 2015 Dec 8;6:8997.
CAS Number
– 16052-06-5
Molecular Weight
– 252.33
Compound Purity
– 98.0
SMILES
– O=S(CCCN1CCN(CCO)CC1)(O)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– H2O : 250 mg/mL (ultrasonic)
Target
– Amyloid-β
Pathway
– Neuronal Signaling
Product type
– Biochemical Assay Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.