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Products Details
Product Description
– Heme Oxygenase-2-IN-1 (Compound 9) is a potent, selective heme oxygenase-2 (HO-2) inhibitor with IC50 values of 0.9 μM and 14.9 μM against HO-2 and HO-1, respectively[1].
Web ID
– HY-147817
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H17N3O2
References
– [1]Floresta G, et al. Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region. Bioorg Chem. 2020 Nov;104:104310.
Molecular Weight
– 319.36
SMILES
– N#CC1=CC=C(COC2=CC=C(C(O)CN3C=CN=C3)C=C2)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Reactive Oxygen Species
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
