Products Details

Product Description

– hDHODH-IN-9 (Compound 3k) is a potent inhibitor of hDHODH with an IC50 of 0.34 μM. hDHODH-IN-9 demonstrates high cytotoxic activity against MCF-7 and A375 cells and good selectivity. hDHODH-IN-9 has the potential for the research of cancer diseases[1].

Web ID

– HY-147788

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C21H21NO4

References

– [1]Petrović MM, et al. Potent human dihydroorotate dehydrogenase inhibitory activity of new quinoline-4-carboxylic acids derived from phenolic aldehydes: Synthesis, cytotoxicity, lipophilicity and molecular docking studies. Bioorg Chem. 2020;105:104373.

CAS Number

– 133676-47-8

Molecular Weight

– 351.40

SMILES

– CCCCOC1=CC=C(C=C1OC)C2=NC3=CC=CC=C3C(C(O)=O)=C2

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Dihydroorotate Dehydrogenase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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