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hDHODH-IN-4
$188 – $1,950
Products Details
Product Description
– hDHODH-IN-4 is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor, with a pIC50 of 7.8 for human recombinant DHODH. hDHODH-IN-4 inhibits measles virus replication, with a pMIC50 of 8.8[1].
Web ID
– HY-128787
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C21H24N4O2
References
– [1]Munier-Lehmann H, et al. Original 2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH). J Med Chem. 2015 Jan 22;58(2):860-77.
CAS Number
– 1644156-56-8
Molecular Weight
– 364.44
Compound Purity
– 99.68
SMILES
– OC(C1=CC=CC=C1)C2=C(C)N(C3=NC=C(C4CC4)C=N3)N=C2OC(C)C
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– Dihydroorotate Dehydrogenase;DNA/RNA Synthesis;Influenza Virus
Pathway
– Anti-infection;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
