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hDHODH-IN-3
$311 – $2,250
Products Details
Product Description
– hDHODH-IN-3 (compound 21d) is a human dihydroorotate dehydrogenase (HsDHODH) inhibitor, inhibits measles virus replication with a pMIC50 value of 8.6[1].
Web ID
– HY-135570
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C18H19BrN4O2
References
– [1]Lucas-Hourani M, et al. Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).J Med Chem. 2015 Jul 23;58(14):5579-98.
CAS Number
– 1644156-80-8
Molecular Weight
– 403.27
Compound Purity
– 99.97
SMILES
– CCC1=CN=C(N2N=C(OCC)C(OC3=CC=CC=C3Br)=C2C)N=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : 33.33 mg/mL (ultrasonic)
Target
– Dihydroorotate Dehydrogenase;DNA/RNA Synthesis;Influenza Virus
Pathway
– Anti-infection;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
