Products Details

Product Description

– hDHODH-IN-14 (compound 14) is a human dihydroorotate dehydrogenase (hDHODH) inhibitor with an IC50 of 0.469 μM[1].

Web ID

– HY-157153

Shipping

– Room temperature

Molecular Formula

– C21H14N2O3S

References

– [1]Xiaoli Ren, et al. Discovery a series of novel inhibitors of human dihydroorotate dehydrogenase: Biological activity evaluation and molecular docking. Chem Biol Drug Des. 2023 Nov 5.

CAS Number

– 881826-17-1

Molecular Weight

– 374.41

SMILES

– O=C(C1=C(/N=C(NC/2=O)SC2=C/C3=CC=CC4=C3C=CC=C4)C=CC=C1)O

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Dihydroorotate Dehydrogenase;DNA/RNA Synthesis

Pathway

– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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