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Products Details
Product Description
– HDAC6-IN-16 (compound 5c) is a histone deacetylase 6 (HDAC6) inhibitor, based on Quinazolin-4(3H)-One. HDAC6-IN-16 exhibits anticancer effect, inhibits colony-forming. And HDAC6-IN-16 arrests cell cycle at G2 phase and induces apoptosis[1].
Web ID
– HY-149371
Shipping
– Room temperature
Molecular Formula
– C23H19N3O3S
References
– [1]Khetmalis YM, et al. Design, Synthesis, and Biological Evaluation of Novel Quinazolin-4(3H)-One-Based Histone Deacetylase 6 (HDAC6) Inhibitors for Anticancer Activity. Int J Mol Sci. 2023 Jul 3;24(13):11044.
Molecular Weight
– 417.48
SMILES
– O=C1N(C2=CC=C(C)C=C2)C(SCC3=CC=C(C(NO)=O)C=C3)=NC4=CC=CC=C41
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;HDAC
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
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