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HDAC6-IN-16
SKU
HY-149371-Get quote
Category Reference compound
Tags Apoptosis;Cell Cycle/DNA Damage;Epigenetics, Apoptosis;HDAC, Cancer
Products Details
Product Description
– HDAC6-IN-16 (compound 5c) is a histone deacetylase 6 (HDAC6) inhibitor, based on Quinazolin-4(3H)-One. HDAC6-IN-16 exhibits anticancer effect, inhibits colony-forming. And HDAC6-IN-16 arrests cell cycle at G2 phase and induces apoptosis[1].
Web ID
– HY-149371
Shipping
– Room temperature
Molecular Formula
– C23H19N3O3S
References
– [1]Khetmalis YM, et al. Design, Synthesis, and Biological Evaluation of Novel Quinazolin-4(3H)-One-Based Histone Deacetylase 6 (HDAC6) Inhibitors for Anticancer Activity. Int J Mol Sci. 2023 Jul 3;24(13):11044.
Molecular Weight
– 417.48
SMILES
– O=C1N(C2=CC=C(C)C=C2)C(SCC3=CC=C(C(NO)=O)C=C3)=NC4=CC=CC=C41
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;HDAC
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.