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Products Details
Product Description
– HDAC6-IN-11 (Compound 9) is a selective HDAC6 inhibitor with the IC50 value of 20.7 nM. HDAC6-IN-11 has more than 300-fold selectivity over HDAC other isoforms. HDAC6-IN-11 shows anti-proliferative activities against cancer cells[1].
Web ID
– HY-150694
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H16N2O4
References
– [1]Shih-Wei Wang, et al. Synthesis and biological evaluation of 2-quinolineacrylamides. Bioorg Med Chem. 2020 Feb 1;28(3):115250.
CAS Number
– 2409072-27-9
Molecular Weight
– 336.34
SMILES
– O=C(NO)/C=C/C1=NC2=CC=C(OC3=CC=C(OC)C=C3)C=C2C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HDAC
Isoform
– HDAC6;HDAC8
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
