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Products Details
Product Description
– HDAC-IN-65 ( compound 6) is a selective histone deacetylase (HDAC) inhibitor with IC50 value of 2.5μM. HDAC-IN-65 is a prodrug with very good bioreductive properties[1].
Web ID
– HY-157152
Shipping
– Room temperature
Molecular Formula
– C30H30N10O5
References
– [1]Mohamed Abdelsalam, et al. Design and synthesis of bioreductive prodrugs of class I histone deacetylase inhibitors and their biological evaluation in virally transfected acute myeloid leukemia cells. Arch Pharm (Weinheim). 2023.
Molecular Weight
– 610.62
SMILES
– O=C(NC1=CC=CC=C1NC(C2=NC=C(N=C2)N3CCN(CC3)CC4=CNC5=C4C=CC=C5)=O)OCC6=CN=C(N6C)[N+]([O-])=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HDAC
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
