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Products Details
Product Description
– HDAC-IN-60 (compound 21a) is a potent histone deacetylase (HDAC) inhibitor. HDAC-IN-60 can promote the intracellular generation of ROS, cause DNA damage, block the cell cycle at G2/M phase, and activate the mitochondria-related apoptotic pathway to induce cell apoptosis[1].
Web ID
– HY-149370
Shipping
– Room temperature
Molecular Formula
– C20H26N2O6
References
– [1]Yang Y, et, al. Design, Synthesis, and Biological Evaluation of Histone Deacetylase Inhibitors Derived from Erianin and Its Derivatives. ChemMedChem. 2023 Jul 3;18(13):e202300108.
CAS Number
– 2944459-58-7
Molecular Weight
– 390.43
SMILES
– COC1=C(OC)C(OC)=CC(CCC2=CC(NCC(NO)=O)=C(OC)C=C2)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;HDAC
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
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