Download Files:
Products Details
Product Description
– hCAXII-IN-5 (compound 6o) is a potent and selective hCAXII inhibitor with Ki values of >10000, >10000, 286.1, 1.0 nM for hCAI, hCAII, hCAIX and hCAXII, respectively[1].
Web ID
– HY-146256
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H22N2O4
References
– [1]Thacker PS, et al. Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem. 2020 May;98:103739.
CAS Number
– 2414629-92-6
Molecular Weight
– 390.43
SMILES
– O=C1C=C(C)C2=C(O1)C=C(OCC3=NOC(C4=CC=C(C(C)(C)C)C=C4)=N3)C=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Isoform
– CA â…¡
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
