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Products Details
Product Description
– hCAXII-IN-4 (compound 5j) is a potent and selective CA XII inhibitor with an Ki value of 6.4 nM for human CA XII[1].
Web ID
– HY-146252
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C22H27N5O6S
References
– [1]Moi D, et al. Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors. Bioorg Chem. 2020 May;98:103728.
CAS Number
– 2414601-79-7
Molecular Weight
– 489.54
SMILES
– O=C(NNC(NCC1=CC=C(OC)C=C1)=O)C2CCN(C(C3=CC=C(S(=O)(N)=O)C=C3)=O)CC2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Isoform
– CA â…¡;CA XII
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
