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hCAIX/XII-IN-7
SKU
HY-156169-Get quote
Category Reference compound
Tags Cancer, Carbonic Anhydrase, Metabolic Enzyme/Protease
Products Details
Product Description
– hCAIX/XII-IN-7 (compound 3e) is a potent hCA IX and XII inhibitor with Kis of 3.2 nM, 9.2 nM, 503.7 nM and 59 nM for hCA I, hCA II, hCA IX and hCA XII, respectively. hCAIX/XII-IN-7 has the potential for hypoxic tumors research[1].
Web ID
– HY-156169
Shipping
– Room temperature
Molecular Formula
– C17H14N6O3S
References
– [1]Suleyman Akocak, et al. Potent and selective carbonic anhydrase inhibition activities of pyrazolones bearing benzenesulfonamides. Bioorg Med Chem Lett. 2023 Oct 15:95:129479.
Molecular Weight
– 382.40
SMILES
– N#CC1=CC=C(N(N=C/2C)C(C2=NNC(C=C3)=CC=C3S(=O)(N)=O)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Isoform
– CA â…¡;CA â…¨;CA I;CA XII
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.