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Products Details
Product Description
– hCAIX-IN-19 is a sulfonamides inhibitor against hCA IX with an inhibition constant (KI ) of 6.2 nM and show good selectivity over hCA I (hCA I/ hCA IX = 117)[1].
Web ID
– HY-157135
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C29H34N4O4S2
References
– [1]Begines P, et al. Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies [J]. Bioorganic & Medicinal Chemistry, 2023, 94: 117467.
Molecular Weight
– 566.73
SMILES
– O=C1N[C@@]2([H])[C@@](CS[C@H]2CCCCC(N(CC3=CC=C(C=CC=C4)C4=C3)CCC5=CC=C(S(=O)(N)=O)C=C5)=O)([H])N1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase;Others
Isoform
– CA â…¨
Pathway
– Metabolic Enzyme/Protease;Others
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
