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hCAIX-IN-13
Products Details
Product Description
– hCAIX-IN-13 (Pt2) is an inhibitor of CAIX (arbonic anhydrase IX) with an IC50 value of 6.57 μM. hCAIX-IN-13 inhibits growth of cancer cells and induces cell apoptosis, it can be used for the research of cancer[1].
Web ID
– HY-151406
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C37H33F3N6O7PtS2
References
– [1]Yang J, et al. NIR phosphorescent cyclometalated platinum (II) complexes with CAIX targeted and nuclear penetration as potent anticancer theragnostic agents. Eur J Med Chem. 2022 Aug 31;243:114702.
CAS Number
– 2813334-66-4
Molecular Weight
– 989.90
SMILES
– O=C(CCCC(NCCC1=CC=C(S(=O)(N)=O)C=C1)=O)NC2=CC3=CC=C[N]4=C3C5=[N]([Pt+2]46[C-]7=C(C8=[N]6C=CC=C8)C=CC=C7)C=CC=C52.FC(F)(S(=O)([O-])=O)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.