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hCAII-IN-7
SKU
HY-144268-Get quote
Category Reference compound
Tags Cancer, Carbonic Anhydrase, Metabolic Enzyme/Protease
Products Details
Product Description
– hCAII-IN-7 (Compound R-13) is a potent human carbonic anhydrase (hCA) inhibitor with Kis of 60.7, 320.7, 2298, and 35.2 nM for hCA I, II, IV and IX, respectively[1].
Web ID
– HY-144268
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H25N3O4S
References
– [1]Chiaramonte N, et al. 2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity. Eur J Med Chem. 2022;228:114026.
Molecular Weight
– 403.50
SMILES
– NS(=O)(C1=CC=C(C=C1)C(N2CCN(C[C@H]2CCO)CC3=CC=CC=C3)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Isoform
– CA â…¡
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.