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Products Details
Product Description
– hCA XII/II/IX-IN-1 (Compound 3) is a potent human carbonic anhydrase (hCA) inhibitor with IC50 values of 2.6, 0.004, 0.005 and 0.001 μM against hCA I, hCA II, hCA IX and hCA XII, respectively. hCA XII/II/IX-IN-1 shows anticancer activity[1].
Web ID
– HY-147799
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H34N4O7S
References
– [1]An R, et al. Discovery of novel artemisinin-sulfonamidehybrids as potential carbonicanhydraseIX inhibitors with improved antiproliferative activities. Bioorg Chem. 2020 Nov;104:104347.
Molecular Weight
– 534.63
SMILES
– C[C@H]1[C@@]2([H])[C@@]34[C@]([H])([C@H]([C@H](O[C@@H]3O[C@@](C)(CC2)OO4)OCCC5=CN(C6=CC=C(S(=O)(N)=O)C=C6)N=N5)C)CC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Isoform
– CA Ⅸ;CA XII
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
