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HBX 19818
$160 – $1,100
Products Details
Product Description
– HBX 19818 is a specific inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 28.1 μM.
Web ID
– HY-17540
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H28ClN3O
References
– [1]Reverdy C, et al. Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme. Chem Biol. 2012 Apr 20;19(4):467-77.
CAS Number
– 1426944-49-1
Molecular Weight
– 421.96
Compound Purity
– 99.35
SMILES
– CN(CCCNC(C1=CC=C(N=C(CCCC2)C2=C3Cl)C3=C1)=O)CC4=CC=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 1M HCl : 100 mg/mL (ultrasonic;adjust pH to 1 with HCl)|DMSO : 20 mg/mL (ultrasonic)
Target
– Deubiquitinase
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
