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Products Details
Product Description
– HBV-IN-21 (Compound II-8b) is an HBV DNA replication inhibitor with an IC50 of 2.2 µM. HBV-IN-21 can interact HBV 4 capsid protein with good affinity (KD = 60.0 μM)[1].
Web ID
– HY-146011
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C17H17FN4OS2
References
– [1]Jia H, et al. Design, diversity-oriented synthesis and biological evaluation of novel heterocycle derivatives as non-nucleoside HBV capsid protein inhibitors. Eur J Med Chem. 2020 Sep 15;202:112495.
CAS Number
– 2460957-52-0
Molecular Weight
– 376.47
SMILES
– O=C(C1=C(CC(C)C)SC(C2=NC=CS2)=N1)NNC3=CC=C(F)C=C3
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis;HBV
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
