Products Details

Product Description

– Haloperidol hydrochloride is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic.

Web ID

– HY-14538A

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C21H24Cl2FNO2

Citations

– Behav Brain Res. 2022 Jan 17;113759.|EMBO Rep. 2022 Jan 17;e53191.|ACS Omega. 2020 Nov 15;5(46):29935-29942.|BMC Endocr Disord. 2021 Nov 23;21(1):235.|Br J Pharmacol. 2021 Apr 26.|Cell Host Microbe. 2023 Nov 8;31(11):1792-1803.e7.|Clin Exp Pharmacol Physiol. 2021 Mar;48(3):370-380.|Environ Sci Technol. 2023 Sep 13.|Eur J Integr Med. 2021, 101322.|Eur J Pharmacol. 2023 Mar 8;175647.|Eur J Pharmacol. 2023 Nov 6:176174.|J Ethnopharmacol. 2021 Mar 9;113994.|PLoS Negl Trop Dis. 2019 Aug 20;13(8):e0007681. 

References

– [1]Joy CB, et al. Haloperidol versus placebo for schizophrenia. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD003082.|[2]Giannini AJ, et al. Acute ketamine intoxication treated by haloperidol: a preliminary study. Am J Ther. 2000 Nov;7(6):389-91.

CAS Number

– 1511-16-6

Molecular Weight

– 412.33

SMILES

– ClC(C=C1)=CC=C1C2(O)CCN(CCCC(C3=CC=C(F)C=C3)=O)CC2.Cl

Clinical Information

– Launched

Research Area

– Neurological Disease; Cancer

Solubility

– 10 mM in DMSO

Target

– Dopamine Receptor

Isoform

– D2 Receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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