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Haloperidol-d4 N-Oxide
SKU
HY-14538S2-1 mg
Category Isotope-Labeled Compounds
Tags Dopamine Receptor;Isotope-Labeled Compounds, GPCR/G Protein;Neuronal Signaling;Others, Neurological Disease
Products Details
Product Description
– Haloperidol-d4 N-Oxide is the deuterium labeled Haloperidol. Haloperidol is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic[1][2].
Web ID
– HY-14538S2
Shipping
– Room temperature
Molecular Formula
– C21H19D4ClFNO3
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Shah NS, et al. Effects of chlorpromazine and haloperidol on the disposition of mescaline-14C in mice. J Pharmacol Exp Ther. 1973 Aug;186(2):297-304|[3]Furuta Y, et al. Effects of enzyme inhibitors of catecholamine metabolism and of haloperidol on the pancreatic secretion induced by L-DOPA and by dopamine in dogs. Br J Pharmacol. 1973 Jan;47(1):77-84
CAS Number
– 1246815-56-4
Molecular Weight
– 395.89
SMILES
– OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)(=O)CC1)C3=C(C(=C(Cl)C(=C3[2H])[2H])[2H])[2H]
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Receptor;Isotope-Labeled Compounds
Isoform
– D2 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling;Others
Product type
– Isotope-Labeled Compounds
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