Products Details

Product Description

– hAChE-IN-4 (Compd 5d) is a potent, blood-brain barrier-permeable hAChE inhibitor with IC50 of 0.25 μM. hAChE-IN-4 can be used in Alzheimer’s disease research[1].

Web ID

– HY-155086

Shipping

– Room temperature

Molecular Formula

– C30H23Cl3N2O3

References

– [1]Salma Fares, et al. Modified Tacrine Derivatives as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease: Synthesis, Biological Evaluation, and Molecular Modeling Study. ACS Omega. 2023 Jul 12;8(29):26012-26034.

Molecular Weight

– 565.87

SMILES

– O=C(C1=CC=C(Cl)C=C1)COC2=CC3=C(C=C2)C(C4=CC=C(Cl)C(Cl)=C4)C5=C(N)C6=C(N=C5O3)CCCC6

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Cholinesterase (ChE)

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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