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hAChE-IN-4
SKU
HY-155086-Get quote
Category Reference compound
Tags Cholinesterase (ChE), Neurological Disease, Neuronal Signaling
Products Details
Product Description
– hAChE-IN-4 (Compd 5d) is a potent, blood-brain barrier-permeable hAChE inhibitor with IC50 of 0.25 μM. hAChE-IN-4 can be used in Alzheimer’s disease research[1].
Web ID
– HY-155086
Shipping
– Room temperature
Molecular Formula
– C30H23Cl3N2O3
References
– [1]Salma Fares, et al. Modified Tacrine Derivatives as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease: Synthesis, Biological Evaluation, and Molecular Modeling Study. ACS Omega. 2023 Jul 12;8(29):26012-26034.
Molecular Weight
– 565.87
SMILES
– O=C(C1=CC=C(Cl)C=C1)COC2=CC3=C(C=C2)C(C4=CC=C(Cl)C(Cl)=C4)C5=C(N)C6=C(N=C5O3)CCCC6
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.